"Textbook on Clinical Research: A Guide for Aspiring Professionals and Professionals" is an essential resource for anyone entering the field of clinical research. This comprehensive guide explores the intricate world of clinical trials and bio-equivalency testing, emphasizing their crucial role in the discovery of groundbreaking treatments and medications. In a world struggling to bridge the gap between healthcare needs and available options, this book highlights the urgent need for more clinical research activities. Drawing on lessons learned during critical times such as the COVID-19 pandemic, the book stresses the importance of developing innovative and safer interventional tools. The book also sheds light on India's evolving landscape of clinical research, offering insights into the impact of separate Clinical Trial Rules and time-bound application reviews. These developments have promoted predictability and transparency in regulatory pathways, aligning with India's journey towards self-reliance in vaccine production and the nation's aspirations for 'Aatmanirbhar Bharat' (self-reliant India). The call for 'vocal for local' further reinforces the demand for skilled professionals to conduct clinical trials and advance clinical research in India. This updated third edition reflects the dynamic changes in the field, introducing new chapters to address the evolving landscape of clinical research. The book is a testament to the author's unwavering dedication and is supported by their family, who have made sacrifices to bring this invaluable resource to aspiring professionals and seasoned experts alike. With its wealth of knowledge and insights, "Textbook on Clinical Research" is an indispensable companion on the journey towards achieving excellence in the field of clinical research.