This book ?Physical Pharmaceutics ? I? presents comprehensively the physicochemical principles of States of matter, Solubility, Surface and interfacial phenomena, Complexation and protein binding, and pH buffers and isotonic solutions to cater to the needs of students undergoing B. Pharmacy course and to help in formulating drugs into suitable pharmaceutical dosage forms. It includes Addendum consisting of some 66 solved problems related to topics covered, which the teachers and the students may find to be supportive in understanding the theory and to bring it into practical use.